THE PHYTOCANNABINOIDES FROM CANNABIS SATIVA L. AN OVERVIEW

Andreea Daniela ONA, Sorin MUNTEAN, Leon MUNTEAN

Abstract


Cannabis sativa is among the first cultivated plants for producing fibres from the stalks and consumption of the seeds. Later, the medicinal properties were discovered. The oldest written record of using cannabis for the medicinal and recreational purposes is from China. Over the time many experimental researches were carried out that emphasize the importance of cannabinoids for human health. The present paper focused to present an overview of the main cannabinoids synthetized in cannabis plant and their medicinal and therapeutic effects. Cannabis has a complex chemical composition including besides cannabinoids (over 100), also terpenoids, sugars, alkaloids, quinones and stilbenoids. Of major importance are two compounds tetrahydrocannabinol (THC) and cannabidiol (CBD). Over the time different researches pointed out the beneficial effect of cannabinoids on a wide range of diseases such as epilepsy, neurological diseases, mental conditions like anxiety and depression, chronic pains and certain forms of cancer. In addition to the important advantages it must be also paid attention to the psychoactive action of the certain cannabinoids that may produce cognitive disturbances, attention disorders, sever panic, can affect the short-term memory, and slow the reaction time. This deficits induced usually by THC can be moderate by using CBD which reduce the psychoactive effect. Considering the similar profile of cannabinoids to other medication, care must be taken to interaction with other drugs and medical conditions.

Keywords


cannabichromene, cannabicyclol, cannabidiol, cannabielsoin, cannabigerol, cannabinodiol, cannabinol, cannabitriol, tetrahydrocannabinol

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