BIOACTIVE SUBSTANCES FROM HOPS – XANTHOHUMOL

Elena Mudura

Abstract


Xanthohumol (3’-[3,3–dimetyl allyl]-2’,4’,4-trihydroxy-6’-methoxychalcone) is the principal prenylated flavonoid of the female inflorescences of the hop plant (‘ Humulus lupulus L.), an ingredient of beer. Xanthohumol has been characterized a cancer chromoprotective agent in in vitro studies, while other prenylate compounds are potent phitoestrogen know to date. These biological activities suggest that prenylflavonoids from hops have potential for application in cancer prevention program, in prevention and treatment of osteoporosis, methabolic sindroms and other farmaceutical applications. Human explosure to xanthohumol and related prenylflavonoids is primarily through beer consumption.

Keywords


Humulus lupulus; hops; prenylflavonoides; xanthohumol

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