Antibacterial Activity of Monolayer Graphene Film to Standardised Staphylococcus Aureus Strains

Gabriel GÂJÂILĂ, Iuliana GÂJÂILĂ, Bogdan TAŞBAC, Andrei AVRAM, Bianca ŢÎNCU, Tiberiu BURINARU


Due to its unique, unanimously recognized properties and biocompatibility, graphene has wide potential applications in biology, biomedical science, environmental agriculture and biotechnology. The antibacterial effect of the graphene is presented in a large number of publications. Most studies reported in the specific literature were aimed mainly at understanding the interaction between graphene and graphene-based materials with cells and bacteria. Even so, there are conflicting results in some cases and there are also numerous controversies regarding the antibacterial effect of monolayer graphene film on different types of substrate.
The study is aimed at testing the antibacterial activity of monolayer graphene film on a copper substrate that was covered with a Staphylococcus aureus culture, Gram-positive bacteria recognized for resilience in external environment. The antibacterial activity of the graphene was evaluated via cell-viability test. It has thus been observed that the bacterial suspension’s phisical contact with the a large-area graphene produces significant disturbances of the microorganism’s vital processes.
This study may provide new insights for the better understanding of antibacterial actions of graphene applied on different substrates and opportunities for biomedical applications.


antibacterial activity, graphene, Staphylococcus aureus

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