THE THERAPEUTIC EFFECTIVENESS OF MEBENDAZOLE IN ANCYLOSTOMOSIS AND STRONGYLOIDOSIS IN DOGS
Abstract
The purpose of the research was to determine the in vivo effectiveness of mebendazole over dog strongyls through Faecal Egg Count Reduction Test (FECRT); the obtained data being statistically interpreted. Ten dogs had been treated with mebendazol; faecal samples were taken before and after treatment over a period of 7 days. The obtained results highlighted an average ante-therapeutic(AT) intensivity of 240 EPG, respectively 370 LPG, and the extensivity being of 100% regardless of the method of calculation. Both values becoming null after the 14th day after treatment. The analysis of the statistical indexes quantified through the level o the EPG show a reduction percentage of 100% in a 14-20 day period post-therapeutic (PT). The value of the probability index calculated through the comparison of AT show significant statistical value. The values of the statistical indexes quantified through LPG shows a reduction percentage of 100% over the length of the experiment the probability index being of 0.00016 regardless of the PT time period. The global analysis of the data obtained by means of FECRT show a good therapeutic effectiveness of mebendazole, with no signs of tolerance in the parasites belonging in the Strongylida Phylum.a) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
b) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
c) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).