THE THERAPEUTIC EFFECTIVENESS OF MEBENDAZOLE IN ANCYLOSTOMOSIS AND STRONGYLOIDOSIS IN DOGS

  • M Cernea University of Agricultural Sciences and Veterinary Medicine, Faculty of Veterinary Medicine, 3-5 Manastur street , 3400, Cluj-Napoca
  • Cristina Cernea
  • Anca Mărculescu
  • S. Trîncă
Keywords: dog, ancylostomosis, strongyloidosis, mebendazole

Abstract

The purpose of the research was to determine the in vivo effectiveness of mebendazole over dog strongyls through Faecal Egg Count Reduction Test (FECRT); the obtained data being statistically interpreted. Ten dogs had been treated with mebendazol; faecal samples were taken before and after treatment over a period of 7 days. The obtained results highlighted an average ante-therapeutic(AT) intensivity of 240 EPG, respectively 370 LPG, and the extensivity being of 100% regardless of the method of calculation. Both values becoming null after the 14th day after treatment. The analysis of the statistical indexes quantified through the level o the EPG show a reduction percentage of 100% in a 14-20 day period post-therapeutic (PT). The value of the probability index calculated through the comparison of AT show significant statistical value. The values of the statistical indexes quantified through LPG shows a reduction percentage of 100% over the length of the experiment the probability index being of 0.00016 regardless of the PT time period. The global analysis of the data obtained by means of FECRT show a good therapeutic effectiveness of mebendazole, with no signs of tolerance in the parasites belonging in the Strongylida Phylum.
Published
2008-12-02
Section
Research Articles