VEGETAL EXTRACTIONS INDUCED, AGE DEPENDENT CHANGES IN CELL-MEDIATED NON-SPECIFIC IMMUNE REACTIVITY

Gh.F. Brudaşcă, Marina Spînu, Carmen Dana Şandru, R. Stefan

Abstract


The evaluation of adjuvant capacities of active principles from Echinacea angustifolia, a cultivated medicinal plant, renown (Percival S.S., 2000; South E.H., Exon J.H., 2001) for its immune activity was done in comparison with that of a similar, alcoholic extraction of Calendula officinalis, a plant widespread in Romania, but less studied as an immune stimulant (Della Logia R. et al., 1994). A comparison between the effects of sc injected (0.5 ml/day/bird) alcoholic Calendula officinalis and Echinacea angustifolia extractions in immunologically immature (19 days old) and mature (47 days and 77 weeks old) chickens (n=7 bird/batch) on total leukocyte numbers and phagocytosis, showed that in 47 days old birds the total leukocyte numbers were lower than in 19 days old birds, in all corresponding batches. In young injected birds, both Calendula and Echinacea extractions were inhibiting on total leukocyte numbers, compared to the solvent control. Meanwhile, in older birds, Calendula was indifferent and Echinacea acted in a stimulating way.

Keywords


age, Calendula oficinalis, Echinacea angustifolia, leukocytes, chickens

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DOI: http://dx.doi.org/10.15835/buasvmcn-vm:63:1-2:2593




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