The Behavior of Candida spp. Strains Isolated from Different Animal Species to Antifungal Drugs

Flore CHIRILĂ, Nicodim FIŢ, Sorin RĂPUNTEAN, George NADĂŞ, Octavian NEGREA


A total number of 28 Candida spp. strains isolated from: cow, man, dog and pigeon from a total of 29 samples processed during the years 2008-2011 in the Microbiology Laboratory of the FVM Cluj-Napoca were examined.Candida spp. strains isolated from dogs suffering from chronic otitis and pharyngeal exudates were sensitive to Ketoconazole, Miconazole and Nystatin. The dog with diffuse alopecia was observed resistance to miconazole.In humans, strains isolated from pharyngeal exudate were sensitive to Nystatin and Miconazole but resistant to Ketoconazole and Fluorocytosine, while in case of the strains isolated from cases of urinary infections antifungal sensitivity varied from case to case (case 1: Miconazole, Nystatin, Ketoconazole, Itraconazole = sensitive, Cotrimoxazole = resistant; case 2: Nystatin = sensitive, ketoconazole, Miconazole, Itraconazole and Cotrimoxazole = resistant.In case of Candida spp. chronic mastitis, sensitivity of the strains was variable from an outbreak of disease to another, in some outbreaks isolates were only sensitive to Nystatin but resistant to Miconazole, Cotrimoxazole, Fluorocytosine, Ketoconazole and Itraconazole, while the others were only sensitive to Miconazole and in others to both. In all cases studied the resistance to Cotrimoxazole, Fluorocytosine, Ketoconazole and Itraconazole was mantained.

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