Adverse and Benefic Effects of Airborne Endotoxins on Human and Poultry Health – Monographic Study

Radu Valentin GROS, Ileana NICHITA, Emil TÎRZIU


Endotoxins are powerful pro-inflammatory agents, producing systemic effects and lung obstruction, even at low level of exposure. It is well known that farmers had a major risk to develop professional respiratory diseases. It was proven that exposure to organic dust could be substantial and can lead to respiratory diseases and to an annual accentuated deprivation of lung functions, endotoxins representing thus a significant respiratory risk. Exposure to airborne endotoxins is associated with a variety of acute (cough, fever, malaise, temporary decrease of lung function) and chronic respiratory symptoms, for example the toxic pneumonia and chronic obstructive bronchitis. It was considered that broilers housed on permanent bedding should present a desensitized immune system, which should demonstrate a better tolerance or resistance to endotoxins exposure, compared to caged broilers.

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