Research Concerning the PCR-RFLP/Eco88I Polymorphism of STAT5A Gene in Romanian Simmental Cattle
Abstract
STAT5 (Signal transducers and activator of transcription) is a member of STATs family that mediates the action of peptide hormones and cytokines within target cells (prolactin signaling can activate transcription of milk protein genes). Using the PCR_RFLP technique and Eco88I enzyme, the C - T nucleotide substitution at position 6853 was detected within exon 7 of the bovine STAT5A gene a population of Romanian Simmental breed. In order to study the relationship between STAT5A/Eco88I polymorphism and milk performance traits, the data for milk production that included milk yield, protein and fat yield, fat and protein percentage were used.
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