Gallic Acid: Derivatives and Biosynthesis, Pharmacological and Therapeutic Effect, Biological Activity

  • Ali Erdem ŞABİK Department of Chemistry and Chemical Processing Technologies, Bahçe Vocational School, University of Osmaniye Korkut Ata, Osmaniye, 80000, Turkey
  • Mustafa SEVİNDİK Faculty of Engineering and Natural Sciences, Osmaniye Korkut Ata University, Osmaniye, 80000, Türkiye
  • Falah Saleh MOHAMMED Faculty of Science, Zakho University, 42-001 Duhok, Iraq
  • Imran UYSAL Bahçe Vocational School, Osmaniye Korkut Ata University, Osmaniye, 80000, Türkiye
  • Celal BAL Oguzeli Vocational School, Gaziantep University, Osmaniye, 27900, Türkiye
Keywords: biological activity, biosynthesis, gallic acid, pharmacology, phenolic compounds

Abstract

Phenolic compounds are important compounds responsible for many therapeutic, pharmacological, and biological activities. They are compounds that do not have nutritional properties but are very important from a medical point of view. In this review, general properties, derivatives and biosynthesis, pharmacological and therapeutic effects, biological activities, and toxic and side effects of gallic acid were reviewed. As a result of the literature research, it has been seen that it has pharmacological and therapeutic effects such as gastrointestinal diseases, cardiovascular disease, neuropsychological and neuroprotective conditions, metabolic diseases, allergic skin, antianxiety, wound healing activity, rheumatoid arthritis, colitis, obesity. It has also been reported to have biological activities such as antioxidant, anti-melanogenic, antimicrobial, anti-ageing, antidiabetic, antiapoptotic, anticancer, anti-inflammatory, hepatoprotective, antiviral, cytotoxic, antidepressant. In this context, it has been determined that gallic acid is an important phenolic compound.

Author Biographies

Mustafa SEVİNDİK, Faculty of Engineering and Natural Sciences, Osmaniye Korkut Ata University, Osmaniye, 80000, Türkiye

Department of Biology

Falah Saleh MOHAMMED, Faculty of Science, Zakho University, 42-001 Duhok, Iraq

Department of Biology

Imran UYSAL, Bahçe Vocational School, Osmaniye Korkut Ata University, Osmaniye, 80000, Türkiye

Department of Food Processing

Published
2024-05-15