The Effect of Lamium album and Lamium purpureum Extracts on Some Blood Parameters under Anakinetic Stress Conditions in Wistar Rats Some Blood Parameters under Anakinetic Stress Conditions in Wistar Rats

  • Ioana Roman Institute of Biological Research Cluj-Napoca, Branch of N.I.R.D.B.S., Bucharest
  • Constantin Puica Institute of Biological Research Cluj-Napoca, Branch of N.I.R.D.B.S., Bucharest
  • Vlad Alexandru Toma Institute of Biological Research Cluj-Napoca, Branch of N.I.R.D.B.S., Bucharest
Keywords: blood parameters, Lamium album, Lamium purpureum, Wistar rat

Abstract

The 17 days subcronic anakinetic stress induced to white Wistar rats by immobilization and darkness has determined TGO, cholesterol and triglycerides values increase, and serum creatinine decreases. Lamium album vegetable extract administration significant increases triglycerides and GOT values and decreases serum creatinine. Administration of both L. album and L. purpureum extracts, in terms of exposure to anakinetic stress, has resulted in a significant increase of the liver transaminases and triglycerides level, decrease of cholesterol and rise of serum creatinine levels. Administration of Lamium purpureum (LP group) vegetable extract has induced the increase of triglyceride values and decrease of cholesterol and serum urea levels. In the SLA group, there was an increase in the red blood cells (RBCs), hematocrit and platelet number, vs. the control group. It has also experienced an increase of the platelets in other treated groups. In the SLP group was noted an increase in the RBCs, hematocrit and platelet number vs. the control group and the decrease in the number of lymphocytes. In comclusion, the vegetal extracts of L. album and L. purpureum (20 mg/100 g b.w.), induced protective modulatory effects on the dynamics of the entire set of functional analyzed parameters.

Author Biographies

Ioana Roman, Institute of Biological Research Cluj-Napoca, Branch of N.I.R.D.B.S., Bucharest
Department of Experimental Biology and Biochemistry, senior researcher, PhD
Constantin Puica, Institute of Biological Research Cluj-Napoca, Branch of N.I.R.D.B.S., Bucharest

Department of Experimental Biology and Biochemistry, senior researcher, PhD

 

Vlad Alexandru Toma, Institute of Biological Research Cluj-Napoca, Branch of N.I.R.D.B.S., Bucharest
Department of Experimental Biology and Biochemistry, res. assistant
Published
2016-05-17