VARIATION OF THE DEUTERIUM CONCENTRATION IN RATS` BLOOD AFTER DEUTERIUM DEPLETED WATER ADMINISTRATION AND INTOXICATION WITH CADMIUM

Mihaela Doina Petcu, Lucia Olariu, Stela Cună, P. Berdea, F. Muselin, Iuliana Creţescu, Mihaela Pup, Ileana Brudiu, Letiţia Stana

Abstract


The effects of cadmium pollution are highlighted in many studies, [7,14]. Cadmium, absorbed within the organism, inhibits the action of some antioxidant enzymes, especially those which contain SH and affect especially the liver and kidneys. The level of deuterium in tap water is 150 ppm and in deuterium depleted water are under 80 ppm. Deuterium depleted water with a deuterium level of 30 ppm has an antioxidant effect on the organism [9, 10]. The present study has asses the effects of deuterium depleted water (30 ppm) on the deuterium blood level in the rats exposed to cadmium (20 ppm Cd/kg administered as CdCl2 solution in a single dose). The intoxication with cadmium modified the blood level of deuterium in the animals and the kidney, liver and spleen weight. The blood level of deuterium was determined through weight spectroscopy with the spectrofotometer SMAD 1. We observed a protective effect of deuterium depleted water on the rat organism, for preventive administration, as well as treatment and the important role in eliminating cadmium

Full Text:

PDF


DOI: http://dx.doi.org/10.15835/buasvmcn-vm:65:1:1248




University of Agricultural Sciences and Veterinary Medicine
3-5 Manastur St., 400372 Cluj-Napoca
Romania
Tel: +40-264-596.384 | Fax: +40-264-593.792
biroupublicatii@usamvcluj.ro