Effect of Lingonberry Extracts on Blood Pressure and Myocardium in Paracetamol Intoxication

  • Ioana ROMAN Institute of Biological Research, Cluj-Napoca, branch of N.I.R.D.S.B. Bucharest, Romania
  • Anca Daniela FARCAS National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania ”Babes-Bolyai” University, Cluj-Napoca, Romania
  • Vlad Alexandru TOMA National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania ”Babes-Bolyai” University, Cluj-Napoca, Romania
Keywords: blood pressure, lingonberry extract, myocardium, Paracetamol, rats.

Abstract

The 15 days of treatment with paracetamol, lingonberry dried extract or hidroalcoholic extract, alone or combined had following effects: blood pressure increases following administration of paracetamol and decreases under treatment with lingonberry extract, more obvious to 3: 1 lingonberry dried extract. Administration of Paracetamol, lingonberry extracts used simple or in combination with Paracetamol does not affect the myocardium histological structure. Histoenzimological there is a slight decrease of SDH activity in the groups P and PLd and an increase in Lha group. CyOx activity is increased in Lha and Ld group.

The dried lingonberry extract has no apparent action on the myocardium instead has antihypertensive properties more obvious than the lingonberry alcoholic extract.

Author Biographies

Ioana ROMAN, Institute of Biological Research, Cluj-Napoca, branch of N.I.R.D.S.B. Bucharest, Romania
Senior Researcher, Depatment of Experimental biology
Anca Daniela FARCAS, National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania ”Babes-Bolyai” University, Cluj-Napoca, Romania

Research Assistant (Molecular and Biomolecular Physics)

PhD Student

Vlad Alexandru TOMA, National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania ”Babes-Bolyai” University, Cluj-Napoca, Romania

Research Assistant (Molecular and Biomolecular Physics)

PhD Student

Published
2017-05-18