PROGNOSIS SIGNIFICANCE OF INTRATUMOR MICROVESSEL DENSITY IN BITCH AND CAT MAMMARY TUMORS
Abstract
The purpose of the study is to see if there could be made an association between mammary tumor angiogenesis and malignancy degree. Our study tried to make a correlation between classical aspect that denote mammary tumor malignancy in bitches and cats, and tumor vascularity. There were realized a quantification of new formed microvessels on microscopic field, and also determined the intratumoral perimeter and aria of sanguine or lymphatic microvessels, utilizing an Olympus image analyzing system. The analyzed microscopic images were magnified of 400x, and vascular perimeter and aria were determined by Olympus DP Soft image analyzing program. The obtained results had been expressed in μm respective μm2. The results had been statistically interpreted, to follow up if the studied parameters could be used in bitch and cats mammary tumor histology grading and in prognosis establishment.
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