CYCLICITY ANALYSIS OF AMINO-ACIDS ON TYPE I COLLAGEN CHAINS

  • Sorana D Bolboacă Iuliu Haţieganu” University of Medicine and Pharmacy, Depart. of Medical Informatics and Biostatistics, 6 Louis Pasteur Street, 400349 Cluj-Napoca
  • L Jäntschi Technical University, Depart. of Chemistry, 103-105 Muncii Bvd, 400641 Cluj-Napoca
Keywords: Amino Acids Sequence, Type I Collagen, Cyclicity, Rank Correlation.

Abstract

The pattern distribution of standard amino acids on type I collagen chains was investigated in rank correlation and autocorrelation analysis. The alpha 1 and alpha 2 chains of five species (Bos taurus, Canis lupus, Danio rerio, Homo sapiens, and Rattus norvegicus) were investigated. A series of PHP programs were created in order to accomplish the aim of the research. The rank correlation analysis showed that a moderate to a very good correlation subsist between ranks of position distribution of standard amino acids in the investigated type I collagen chains on all species. The autocorrelation analysis revealed that the amino acid sequences on type I collagen chains have not a repeating patters.

Author Biographies

Sorana D Bolboacă, Iuliu Haţieganu” University of Medicine and Pharmacy, Depart. of Medical Informatics and Biostatistics, 6 Louis Pasteur Street, 400349 Cluj-Napoca
Biotechnologies
L Jäntschi, Technical University, Depart. of Chemistry, 103-105 Muncii Bvd, 400641 Cluj-Napoca
Biotechnologies
Published
2008-12-15